K62E (p.Lys62Glu) variant of CCR5 (C-C chemokine receptor type 5)
K62E (p.Lys62Glu) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
K62E (p.Lys62Glu) variant details
- p.Lys62Glu
- TOPMed rs1357139013
- Missense
- Variant Prioritization Score for Impact Estimate 0.243
- REVEL 0.17
- CADD 22.70
- PolyPhen-2 0.96
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available