K59R (p.Lys59Arg) variant of CCR5 (C-C chemokine receptor type 5)
K59R (p.Lys59Arg) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
K59R (p.Lys59Arg) variant details
- p.Lys59Arg
- gnomAD 3-46373078-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- REVEL 0.11
- MetaLR 0.13
- MetaSVM -1.00
- CADD 18.80
- PolyPhen-2 0.51
- SIFT 0.15
- Population evidence available
- Structural context available
- Literature evidence available