K59E (p.Lys59Glu) variant of CCR5 (C-C chemokine receptor type 5)
K59E (p.Lys59Glu) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
K59E (p.Lys59Glu) variant details
- p.Lys59Glu
- gnomAD 3-46373077-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.392
- REVEL 0.28
- MetaLR 0.20
- MetaSVM -0.87
- CADD 23.00
- PolyPhen-2 0.94
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available