K22T (p.Lys22Thr) variant of CCR5 (C-C chemokine receptor type 5)
K22T (p.Lys22Thr) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
K22T (p.Lys22Thr) variant details
- p.Lys22Thr
- ExAC rs776432250
- gnomAD rs776432250
- Missense
- Variant Prioritization Score for Impact Estimate 0.319
- REVEL 0.19
- CADD 21.40
- PolyPhen-2 0.43
- SIFT 0.03
- Most common in the South Asian population (allele frequency 0.00013)
- Structural context available