I67T (p.Ile67Thr) variant of CCR5 (C-C chemokine receptor type 5)
I67T (p.Ile67Thr) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
I67T (p.Ile67Thr) variant details
- p.Ile67Thr
- 1000Genomes rs199722561
- Missense
- Variant Prioritization Score for Impact Estimate 0.666
- REVEL 0.69
- CADD 24.90
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the 1KG:CHB population (allele frequency 0.0049)
- Structural context available