I56L (p.Ile56Leu) variant of CCR5 (C-C chemokine receptor type 5)
I56L (p.Ile56Leu) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
I56L (p.Ile56Leu) variant details
- p.Ile56Leu
- gnomAD rs1261999587
- Missense
- Variant Prioritization Score for Impact Estimate 0.0718
- REVEL 0.06
- CADD 3.31
- PolyPhen-2 0.14
- SIFT 0.28
- Most common in the REMAINING population (allele frequency 5e-05)
- Structural context available