I54T (p.Ile54Thr) variant of CCR5 (C-C chemokine receptor type 5)
I54T (p.Ile54Thr) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
I54T (p.Ile54Thr) variant details
- p.Ile54Thr
- ExAC rs767459001
- TOPMed rs767459001
- gnomAD rs767459001
- Missense
- Variant Prioritization Score for Impact Estimate 0.0999
- REVEL 0.06
- CADD 12.70
- PolyPhen-2 0.03
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available