I54N (p.Ile54Asn) variant of CCR5 (C-C chemokine receptor type 5)
I54N (p.Ile54Asn) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
I54N (p.Ile54Asn) variant details
- p.Ile54Asn
- ExAC rs767459001
- TOPMed rs767459001
- gnomAD rs767459001
- Missense
- Variant Prioritization Score for Impact Estimate 0.193
- REVEL 0.16
- CADD 22.40
- PolyPhen-2 0.81
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available