I28V (p.Ile28Val) variant of CCR5 (C-C chemokine receptor type 5)
I28V (p.Ile28Val) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
I28V (p.Ile28Val) variant details
- p.Ile28Val
- gnomAD 3-46372984-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0847
- REVEL 0.03
- MetaLR 0.10
- MetaSVM -0.99
- CADD 4.29
- PolyPhen-2 0.00
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available