I12V (p.Ile12Val) variant of CCR5 (C-C chemokine receptor type 5)
I12V (p.Ile12Val) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
I12V (p.Ile12Val) variant details
- p.Ile12Val
- ExAC rs755442066
- gnomAD rs755442066
- Missense
- Variant Prioritization Score for Impact Estimate 0.0624
- REVEL 0.07
- CADD 0.03
- PolyPhen-2 0.07
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available