G47S (p.Gly47Ser) variant of CCR5 (C-C chemokine receptor type 5)
G47S (p.Gly47Ser) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data, published literature, and structural context.
G47S (p.Gly47Ser) variant details
- p.Gly47Ser
- gnomAD 3-46373041-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.696
- REVEL 0.67
- MetaLR 0.54
- MetaSVM 0.45
- CADD 26.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available