F45S (p.Phe45Ser) variant of CCR5 (C-C chemokine receptor type 5)
F45S (p.Phe45Ser) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
F45S (p.Phe45Ser) variant details
- p.Phe45Ser
- Ensembl rs1559567874
- Missense
- Variant Prioritization Score for Impact Estimate 0.224
- REVEL 0.09
- CADD 19.70
- PolyPhen-2 0.01
- SIFT 0.04
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available