F43S (p.Phe43Ser) variant of CCR5 (C-C chemokine receptor type 5)
F43S (p.Phe43Ser) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
F43S (p.Phe43Ser) variant details
- p.Phe43Ser
- gnomAD 3-46373030-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.102
- REVEL 0.02
- MetaLR 0.08
- MetaSVM -1.03
- CADD 13.90
- PolyPhen-2 0.02
- SIFT 0.10
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available
- Literature evidence available