F41L (p.Phe41Leu) variant of CCR5 (C-C chemokine receptor type 5)
F41L (p.Phe41Leu) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
F41L (p.Phe41Leu) variant details
- p.Phe41Leu
- gnomAD 3-46373023-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.255
- REVEL 0.13
- MetaLR 0.33
- MetaSVM -0.30
- CADD 20.20
- PolyPhen-2 0.17
- SIFT 0.13
- Population evidence available
- Structural context available
- Literature evidence available