D66V (p.Asp66Val) variant of CCR5 (C-C chemokine receptor type 5)
D66V (p.Asp66Val) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
D66V (p.Asp66Val) variant details
- p.Asp66Val
- gnomAD 3-46373099-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.594
- REVEL 0.64
- MetaLR 0.37
- MetaSVM 0.09
- CADD 24.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available