D2V (p.Asp2Val) variant of CCR5 (C-C chemokine receptor type 5)
D2V (p.Asp2Val) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
D2V (p.Asp2Val) variant details
- p.Asp2Val
- gnomAD 3-46372907-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.361
- REVEL 0.28
- CADD 24.10
- PolyPhen-2 0.56
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available