D2G (p.Asp2Gly) variant of CCR5 (C-C chemokine receptor type 5)
D2G (p.Asp2Gly) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
D2G (p.Asp2Gly) variant details
- p.Asp2Gly
- gnomAD 3-46372907-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.09
- CADD 22.90
- PolyPhen-2 0.01
- SIFT 0.04
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available