D2E (p.Asp2Glu) variant of CCR5 (C-C chemokine receptor type 5)
D2E (p.Asp2Glu) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
D2E (p.Asp2Glu) variant details
- p.Asp2Glu
- gnomAD rs1365309969
- Missense
- Variant Prioritization Score for Impact Estimate 0.0643
- REVEL 0.07
- CADD 0.28
- PolyPhen-2 0.01
- SIFT 0.27
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available