D11A (p.Asp11Ala) variant of CCR5 (C-C chemokine receptor type 5)
D11A (p.Asp11Ala) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
D11A (p.Asp11Ala) variant details
- p.Asp11Ala
- gnomAD 3-46372934-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.36
- REVEL 0.30
- CADD 17.60
- PolyPhen-2 0.07
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available