C58W (p.Cys58Trp) variant of CCR5 (C-C chemokine receptor type 5)
C58W (p.Cys58Trp) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
C58W (p.Cys58Trp) variant details
- p.Cys58Trp
- gnomAD rs1211101172
- Missense
- Variant Prioritization Score for Impact Estimate 0.446
- REVEL 0.47
- CADD 22.80
- PolyPhen-2 0.93
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available