C20G (p.Cys20Gly) variant of CCR5 (C-C chemokine receptor type 5)
C20G (p.Cys20Gly) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
C20G (p.Cys20Gly) variant details
- p.Cys20Gly
- gnomAD 3-46372960-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.572
- REVEL 0.53
- CADD 25.10
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available