C20* (p.Cys20Ter) variant of CCR5 (C-C chemokine receptor type 5)
C20* (p.Cys20Ter) in CCR5 (C-C chemokine receptor type 5) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
C20* (p.Cys20Ter) variant details
- p.Cys20Ter
- ExAC rs760428955
- TOPMed rs760428955
- gnomAD rs760428955
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.449
- CADD 27.20
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available