A30D (p.Ala30Asp) variant of CCR5 (C-C chemokine receptor type 5)
A30D (p.Ala30Asp) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
A30D (p.Ala30Asp) variant details
- p.Ala30Asp
- TOPMed rs1701685697
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.23
- CADD 21.50
- PolyPhen-2 0.47
- SIFT 0.01
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available