V35L (p.Val35Leu) variant of CCNE1 (G1/S-specific cyclin-E1)
V35L (p.Val35Leu) in CCNE1 (G1/S-specific cyclin-E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
V35L (p.Val35Leu) variant details
- p.Val35Leu
- gnomAD 19-29812768-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.423
- REVEL 0.18
- MetaLR 0.24
- MetaSVM -0.75
- CADD 32.00
- PolyPhen-2 0.99
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available