V35G (p.Val35Gly) variant of CCNE1 (G1/S-specific cyclin-E1)
V35G (p.Val35Gly) in CCNE1 (G1/S-specific cyclin-E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
V35G (p.Val35Gly) variant details
- p.Val35Gly
- gnomAD 19-29812769-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.396
- REVEL 0.22
- MetaLR 0.25
- MetaSVM -0.73
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the South Asian population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available