T15S (p.Thr15Ser) variant of CCNE1 (G1/S-specific cyclin-E1)
T15S (p.Thr15Ser) in CCNE1 (G1/S-specific cyclin-E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
T15S (p.Thr15Ser) variant details
- p.Thr15Ser
- gnomAD 19-29812708-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0749
- REVEL 0.01
- CADD 12.50
- PolyPhen-2 0.00
- SIFT 0.49
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available