R27G (p.Arg27Gly) variant of CCNE1 (G1/S-specific cyclin-E1)
R27G (p.Arg27Gly) in CCNE1 (G1/S-specific cyclin-E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
R27G (p.Arg27Gly) variant details
- p.Arg27Gly
- ExAC rs776712074
- gnomAD rs776712074
- Missense
- Variant Prioritization Score for Impact Estimate 0.423
- REVEL 0.23
- CADD 27.10
- PolyPhen-2 1.00
- SIFT 0.03
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available