M46T (p.Met46Thr) variant of CCNE1 (G1/S-specific cyclin-E1)
M46T (p.Met46Thr) in CCNE1 (G1/S-specific cyclin-E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
M46T (p.Met46Thr) variant details
- p.Met46Thr
- ExAC rs764828115
- TOPMed rs764828115
- gnomAD rs764828115
- Missense
- Variant Prioritization Score for Impact Estimate 0.227
- REVEL 0.07
- CADD 22.80
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available