K32R (p.Lys32Arg) variant of CCNE1 (G1/S-specific cyclin-E1)
K32R (p.Lys32Arg) in CCNE1 (G1/S-specific cyclin-E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
K32R (p.Lys32Arg) variant details
- p.Lys32Arg
- gnomAD 19-29812760-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.368
- REVEL 0.16
- MetaLR 0.29
- MetaSVM -0.53
- CADD 33.00
- PolyPhen-2 0.99
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available