G21S (p.Gly21Ser) variant of CCNE1 (G1/S-specific cyclin-E1)
G21S (p.Gly21Ser) in CCNE1 (G1/S-specific cyclin-E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
G21S (p.Gly21Ser) variant details
- p.Gly21Ser
- TOPMed rs1275105376
- gnomAD rs1275105376
- Missense
- Variant Prioritization Score for Impact Estimate 0.121
- REVEL 0.03
- CADD 15.30
- PolyPhen-2 0.00
- SIFT 0.56
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available