G21D (p.Gly21Asp) variant of CCNE1 (G1/S-specific cyclin-E1)
G21D (p.Gly21Asp) in CCNE1 (G1/S-specific cyclin-E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
G21D (p.Gly21Asp) variant details
- p.Gly21Asp
- gnomAD 19-29812727-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.07
- CADD 17.40
- PolyPhen-2 0.06
- SIFT 0.23
- Population evidence available
- Structural context available
- Literature evidence available