G21C (p.Gly21Cys) variant of CCNE1 (G1/S-specific cyclin-E1)
G21C (p.Gly21Cys) in CCNE1 (G1/S-specific cyclin-E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
G21C (p.Gly21Cys) variant details
- p.Gly21Cys
- gnomAD 19-29812726-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.204
- REVEL 0.12
- CADD 23.90
- PolyPhen-2 0.59
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available