F24L (p.Phe24Leu) variant of CCNE1 (G1/S-specific cyclin-E1)
F24L (p.Phe24Leu) in CCNE1 (G1/S-specific cyclin-E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
F24L (p.Phe24Leu) variant details
- p.Phe24Leu
- ExAC rs778672861
- gnomAD rs778672861
- Missense
- Variant Prioritization Score for Impact Estimate 0.117
- REVEL 0.01
- CADD 14.00
- PolyPhen-2 0.00
- SIFT 0.77
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available