D41N (p.Asp41Asn) variant of CCNE1 (G1/S-specific cyclin-E1)
D41N (p.Asp41Asn) in CCNE1 (G1/S-specific cyclin-E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
D41N (p.Asp41Asn) variant details
- p.Asp41Asn
- gnomAD rs1225643119
- Missense
- Variant Prioritization Score for Impact Estimate 0.445
- REVEL 0.15
- CADD 33.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available