A33V (p.Ala33Val) variant of CCNE1 (G1/S-specific cyclin-E1)
A33V (p.Ala33Val) in CCNE1 (G1/S-specific cyclin-E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
A33V (p.Ala33Val) variant details
- p.Ala33Val
- gnomAD rs1186891855
- Missense
- Variant Prioritization Score for Impact Estimate 0.438
- REVEL 0.12
- CADD 34.00
- PolyPhen-2 0.71
- SIFT 0.05
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available