A26S (p.Ala26Ser) variant of CCNE1 (G1/S-specific cyclin-E1)
A26S (p.Ala26Ser) in CCNE1 (G1/S-specific cyclin-E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
A26S (p.Ala26Ser) variant details
- p.Ala26Ser
- TOPMed rs1250060364
- gnomAD rs1250060364
- Missense
- Variant Prioritization Score for Impact Estimate 0.139
- REVEL 0.03
- CADD 15.30
- PolyPhen-2 0.00
- SIFT 0.33
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available