Y38F (p.Tyr38Phe) variant of CCND3 (G1/S-specific cyclin-D3)
Y38F (p.Tyr38Phe) in CCND3 (G1/S-specific cyclin-D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
Y38F (p.Tyr38Phe) variant details
- p.Tyr38Phe
- TOPMed rs1472629592
- gnomAD rs1472629592
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.11
- CADD 23.10
- PolyPhen-2 0.29
- SIFT 0.19
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available