W63R (p.Trp63Arg) variant of CCND3 (G1/S-specific cyclin-D3)
W63R (p.Trp63Arg) in CCND3 (G1/S-specific cyclin-D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
W63R (p.Trp63Arg) variant details
- p.Trp63Arg
- TOPMed rs1343937602
- gnomAD rs1343937602
- Missense
- Variant Prioritization Score for Impact Estimate 0.512
- REVEL 0.38
- CADD 33.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available