R87H (p.Arg87His) variant of CCND3 (G1/S-specific cyclin-D3)
R87H (p.Arg87His) in CCND3 (G1/S-specific cyclin-D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
R87H (p.Arg87His) variant details
- p.Arg87His
- ExAC rs780693475
- gnomAD rs780693475
- Missense
- Variant Prioritization Score for Impact Estimate 0.733
- REVEL 0.66
- CADD 32.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available