R72C (p.Arg72Cys) variant of CCND3 (G1/S-specific cyclin-D3)
R72C (p.Arg72Cys) in CCND3 (G1/S-specific cyclin-D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
R72C (p.Arg72Cys) variant details
- p.Arg72Cys
- Ensembl rs1775967404
- Missense
- Variant Prioritization Score for Impact Estimate 0.529
- REVEL 0.30
- CADD 33.00
- PolyPhen-2 0.94
- SIFT 0.00
- Most common in the East Asian population (allele frequency 7.6e-05)
- Structural context available