R33L (p.Arg33Leu) variant of CCND3 (G1/S-specific cyclin-D3)
R33L (p.Arg33Leu) in CCND3 (G1/S-specific cyclin-D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
R33L (p.Arg33Leu) variant details
- p.Arg33Leu
- ExAC rs755426354
- TOPMed rs755426354
- gnomAD rs755426354
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.07
- CADD 22.10
- PolyPhen-2 0.00
- SIFT 0.27
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available