R20Q (p.Arg20Gln) variant of CCND3 (G1/S-specific cyclin-D3)
R20Q (p.Arg20Gln) in CCND3 (G1/S-specific cyclin-D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
R20Q (p.Arg20Gln) variant details
- p.Arg20Gln
- TOPMed rs1202872573
- gnomAD rs1202872573
- Missense
- Variant Prioritization Score for Impact Estimate 0.181
- REVEL 0.02
- CADD 16.50
- PolyPhen-2 0.00
- SIFT 0.60
- Most common in the African/African-American population (allele frequency 3.2e-05)
- Structural context available