R14Q (p.Arg14Gln) variant of CCND3 (G1/S-specific cyclin-D3)
R14Q (p.Arg14Gln) in CCND3 (G1/S-specific cyclin-D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
R14Q (p.Arg14Gln) variant details
- p.Arg14Gln
- gnomAD rs1373858958
- Missense
- Variant Prioritization Score for Impact Estimate 0.385
- REVEL 0.09
- CADD 29.60
- PolyPhen-2 0.97
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available