P19L (p.Pro19Leu) variant of CCND3 (G1/S-specific cyclin-D3)
P19L (p.Pro19Leu) in CCND3 (G1/S-specific cyclin-D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
P19L (p.Pro19Leu) variant details
- p.Pro19Leu
- gnomAD rs956471154
- Missense
- Variant Prioritization Score for Impact Estimate 0.28
- REVEL 0.07
- CADD 24.80
- PolyPhen-2 0.09
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 3.2e-05)
- Structural context available