M107L (p.Met107Leu) variant of CCND3 (G1/S-specific cyclin-D3)
M107L (p.Met107Leu) in CCND3 (G1/S-specific cyclin-D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
M107L (p.Met107Leu) variant details
- p.Met107Leu
- cosmic curated COSV10530
- ExAC rs745542165
- gnomAD rs745542165
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.20
- CADD 22.60
- PolyPhen-2 0.00
- SIFT 0.31
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available