L3V (p.Leu3Val) variant of CCND3 (G1/S-specific cyclin-D3)
L3V (p.Leu3Val) in CCND3 (G1/S-specific cyclin-D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
L3V (p.Leu3Val) variant details
- p.Leu3Val
- TOPMed rs746833245
- gnomAD rs746833245
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- REVEL 0.20
- CADD 23.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 4.8e-06)
- Structural context available