I121M (p.Ile121Met) variant of CCND3 (G1/S-specific cyclin-D3)
I121M (p.Ile121Met) in CCND3 (G1/S-specific cyclin-D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
I121M (p.Ile121Met) variant details
- p.Ile121Met
- cosmic curated COSV65912
- ExAC rs765106114
- TOPMed rs765106114
- gnomAD rs765106114
- Missense
- Variant Prioritization Score for Impact Estimate 0.22
- REVEL 0.07
- CADD 22.80
- PolyPhen-2 0.04
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available