F45L (p.Phe45Leu) variant of CCND3 (G1/S-specific cyclin-D3)
F45L (p.Phe45Leu) in CCND3 (G1/S-specific cyclin-D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
F45L (p.Phe45Leu) variant details
- p.Phe45Leu
- ExAC rs762696595
- TOPMed rs762696595
- gnomAD rs762696595
- Missense
- Variant Prioritization Score for Impact Estimate 0.304
- REVEL 0.17
- CADD 28.60
- PolyPhen-2 0.91
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available