E7D (p.Glu7Asp) variant of CCND3 (G1/S-specific cyclin-D3)
E7D (p.Glu7Asp) in CCND3 (G1/S-specific cyclin-D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
E7D (p.Glu7Asp) variant details
- p.Glu7Asp
- gnomAD rs1353591902
- Missense
- Variant Prioritization Score for Impact Estimate 0.311
- REVEL 0.12
- CADD 24.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00025)
- Structural context available