E51G (p.Glu51Gly) variant of CCND3 (G1/S-specific cyclin-D3)
E51G (p.Glu51Gly) in CCND3 (G1/S-specific cyclin-D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
E51G (p.Glu51Gly) variant details
- p.Glu51Gly
- TOPMed rs1259065453
- gnomAD rs1259065453
- Missense
- Variant Prioritization Score for Impact Estimate 0.409
- REVEL 0.21
- CADD 32.00
- PolyPhen-2 0.83
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available